Wood-fired pies made with imported Italian ingredients and hand-crafted dough right here in Germantown.
DeSano Pizzeria Napoletana brings the soul of Naples to Nashville’s historic Germantown neighborhood. Every pie starts with dough made daily on-site by Rob, who treats each batch like an art form. Using 00 flour, San Marzano tomatoes, and fior di latte imported straight from Italy, the pizzas emerge from the 900-degree wood-fired oven with perfectly blistered edges and a tender, airy center. The open kitchen lets guests watch the magic happen while the warm, rustic dining room—with reclaimed wood and terracotta tones—feels like an Italian neighborhood trattoria. Whether you’re grabbing a quick slice at the counter or lingering over a bottle of Chianti, every detail is designed to transport you straight to Southern Italy without ever leaving 4th Avenue North.
Dine-in, carryout, and delivery available daily. Our wood-fired menu features twelve-inch and eighteen-inch pies ranging from the classic Margherita to bold seasonal creations like Hot Honey and Truffle Mushroom. We also offer gluten-free dough, vegan cheese, and a robust kids’ menu. Need to feed a crowd? Our catering packages include build-your-own pizza stations, antipasto platters, and fresh salads delivered hot to your door or office. Private dining for up to 40 guests is available in our back room—perfect for rehearsal dinners, birthday celebrations, or team lunches. Order online for contactless pickup or schedule a delivery through our partnership with local drivers.
Take a look at our space and what we have to offer
Don't just take our word for it - hear from our satisfied customers
Yes, we have a dedicated gluten-free dough and vegan cheese made from cashew milk. Both cook in the same 900-degree oven, so trace gluten may be present.
We keep a walk-in list and also accept reservations for parties of six or more. Peak hours (6–8 pm) usually see a 20–30 minute wait.
Absolutely. Order directly through desanopizza.com or our app for carryout and local delivery. We also partner with DoorDash and Uber Eats.
Yes. Our catering menu includes hot pizza boxes, salad platters, and antipasto trays. We can deliver or set up a full pizza station on-site for groups of 20–200.
Street parking is available on 4th Ave and nearby side streets. There’s also a paid lot one block north at 5th and Monroe.
Our imported Italian wood-fired oven reaches 900 degrees and cooks each pie in roughly 90 seconds for the perfect blistered crust.
Hand-picked local businesses near here, surfaced by NearByMeNow. Click any card to explore the full directory.